Bus transportation is provided by public districts within a 10-mile radius of Greensburg Central Catholic. These districts include: Greensburg-Salem, Hempfield, Latrobe, Norwin, Penn Trafford, Yough, Derry and Ligonier. Additionally, transportation is provided to students living in Apollo, Armstrong, Belle Vernon, Burrell, Connellsville, Franklin Regional, Frazier, Gateway, Jeannette, Kiski, Leechburg, Mount Pleasant, Plum, Ringgold, and Southmoreland.
Although there is no after-school student activity bus transportation, coaches and moderators are sensitive to the travel needs of students.